Nothing can be more irritating than a stuck pixel in the center of your screen.  The folks over at makeuseof.com have a list of fix it techniques that can fix that; from their site:

"A dead or stuck pixel on an LCD screen or TFT can be incredibly annoying. You’ll be staring at it for days on end, wondering for how long you’ll be without your screen or maybe your entire laptop if you decided to turn it in for repair or replacement. All that grieve over something as unimportant, yet highly irritating as a malfunctioning pixel."

Check out the rest of this screen fix:  http://www.makeuseof.com/tag/best-soft

ware-solutions-to-fix-a-stuck-pixel-on-your-lcd-monitor/